Genital abnormalities and underdevelopment are most common in males.Physical retardation caused by growth hormone deficiencies or difficulty in feeding can be detected in the first six months of the child’s life. Intellectual retardation can cause low IQ, near-normal IQ, or sometimes result in severe disabilities. Retardation can be intellectual or physical.Heart defects also occur in 75% of newborns affected by the Syndrome, and are most frequently in the form of a hole in the heart. The loss of hearing occurs in 97% of diagnosed children, and results from an underdeveloped cranial nerve.
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